Search on: INTERLEUKIN 1 RECEPTOR ANTAGONIST PROTEIN 
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Descriptor English:   Interleukin 1 Receptor Antagonist Protein 
Descriptor Spanish:   Proteína Antagonista del Receptor de Interleucina 1 
Descriptor Portuguese:   Proteína Antagonista do Receptor de Interleucina 1 
Tree Number:   D12.644.276.374.460
D12.776.467.374.460
D23.529.374.460
Definition English:   A ligand that binds to but fails to activate the INTERLEUKIN 1 RECEPTOR. It plays an inhibitory role in the regulation of INFLAMMATION and FEVER. Several isoforms of the protein exist due to multiple ALTERNATIVE SPLICING of its mRNA. 
Pharmacological Action:   Antirheumatic Agents
 
History Note English:   2007 
Allowable Qualifiers English:  
AD administration & dosage AE adverse effects
AG agonists AN analysis
AI antagonists & inhibitors BI biosynthesis
BL blood CF cerebrospinal fluid
CS chemical synthesis CH chemistry
CL classification CT contraindications
DF deficiency DE drug effects
EC economics GE genetics
HI history IM immunology
IP isolation & purification ME metabolism
PK pharmacokinetics PD pharmacology
PH physiology PO poisoning
RE radiation effects SE secretion
ST standards SD supply & distribution
TU therapeutic use TO toxicity
UL ultrastructure UR urine
Record Number:   52275 
Unique Identifier:   D053590 

Occurrence in VHL:
 

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